Deca-Durabolin (nandrolone decanoate)
Muscle & Strength · Injectable 19-nor steroid
Tier C+
Bottom line
Read Off Label grades Deca-Durabolin (nandrolone decanoate) as C+ (5.6/10) based on strong evidence, high benefit magnitude, and a high-risk safety profile.
Famously 'joint-friendly' — many anecdotes of subjective joint relief.
Typical use: Clinical: 50-100 mg IM every 2-4 weeks; illicit: 200-600 mg/week — Schedule III US; Rx for anemia/wasting in some countries; banned sport.
What this is
Famously 'joint-friendly' — many anecdotes of subjective joint relief. Very slow release (half-life ~6-15 days). Long detection window in sport testing. Recovery of HPG axis can take 6-18 months post-cycle.
Mechanism
Nandrolone (19-nortestosterone) with long decanoate ester; AR agonist with reduced DHT conversion; progestogenic activity; joint/collagen synthesis benefits
Dose & route
Clinical: 50-100 mg IM every 2-4 weeks; illicit: 200-600 mg/week
Citations
- https://pubmed.ncbi.nlm.nih.gov/9541589/
- https://pubmed.ncbi.nlm.nih.gov/15615126/
- https://pubmed.ncbi.nlm.nih.gov/14745085/
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Common questions
- Does Deca-Durabolin (nandrolone decanoate) work?
- Read Off Label rates the evidence for Deca-Durabolin (nandrolone decanoate) as Strong and the benefit magnitude as high, producing an overall grade of C+ (5.6/10). Famously 'joint-friendly' — many anecdotes of subjective joint relief.
- Is Deca-Durabolin (nandrolone decanoate) safe?
- Deca-Durabolin (nandrolone decanoate) has a high risk profile in published human data. Legal status: Schedule III US; Rx for anemia/wasting in some countries; banned sport. This is not medical advice — see the disclaimer.
- What is the typical dose for Deca-Durabolin (nandrolone decanoate)?
- Clinical: 50-100 mg IM every 2-4 weeks; illicit: 200-600 mg/week
- How does Deca-Durabolin (nandrolone decanoate) work?
- Nandrolone (19-nortestosterone) with long decanoate ester; AR agonist with reduced DHT conversion; progestogenic activity; joint/collagen synthesis benefits
This is an independent synthesis of published research by a non-clinician. Scores are opinions supported by citations, not prescriptions. See the full disclaimer and methodology for how this score was produced and what it does and doesn't mean.