Rankings / Muscle & Strength

CJC-1295 (with/without DAC)

Muscle & Strength · GHRH analog

Tier C-

Reviewed by Read Off Label · Last reviewed · How we grade

gh-axisbanned
4.1 / 10
Tier C-
Ev 3 Bn 5 Sf 5

Bottom line

Read Off Label grades CJC-1295 (with/without DAC) as C- (4.1/10) based on weak evidence, med benefit magnitude, and a med-risk safety profile.

Originating company ConjuChem discontinued clinical development.

Typical use: CJC-1295 with DAC: 1-2 mg/week subQ; without DAC: 100-300 mcg 1-3x daily — Research peptide; not FDA-approved; banned sport.

What this is

Originating company ConjuChem discontinued clinical development. Popular in peptide stacks combined with GHRP-6, GHRP-2, or Ipamorelin. 'With DAC' vs 'without DAC' distinction important — DAC flattens physiological GH pulsatility which may be disadvantageous.

Mechanism

Tetra-substituted GHRH(1-29) analog; DAC (drug affinity complex) version binds albumin for multi-day half-life; stimulates pituitary GH release in pulsatile (non-DAC) or tonic (DAC) manner

Dose & route

CJC-1295 with DAC: 1-2 mg/week subQ; without DAC: 100-300 mcg 1-3x daily

Citations

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Common questions

Does CJC-1295 (with/without DAC) work?
Read Off Label rates the evidence for CJC-1295 (with/without DAC) as Weak and the benefit magnitude as med, producing an overall grade of C- (4.1/10). Originating company ConjuChem discontinued clinical development.
Is CJC-1295 (with/without DAC) safe?
CJC-1295 (with/without DAC) has a med risk profile in published human data. Legal status: Research peptide; not FDA-approved; banned sport. This is not medical advice — see the disclaimer.
What is the typical dose for CJC-1295 (with/without DAC)?
CJC-1295 with DAC: 1-2 mg/week subQ; without DAC: 100-300 mcg 1-3x daily
How does CJC-1295 (with/without DAC) work?
Tetra-substituted GHRH(1-29) analog; DAC (drug affinity complex) version binds albumin for multi-day half-life; stimulates pituitary GH release in pulsatile (non-DAC) or tonic (DAC) manner

This is an independent synthesis of published research by a non-clinician. Scores are opinions supported by citations, not prescriptions. See the full disclaimer and methodology for how this score was produced and what it does and doesn't mean.