Rankings / Weight Loss — Other
CLA (conjugated linoleic acid)
Weight loss · Fatty acid
Tier C
otc
5.1 / 10
Tier C
Ev 4.5 Bn 2.0 Sf 7.0 Ax 10.0
What this is
Early enthusiasm has faded. Modest fat loss (~0.5-1 kg over 12+ weeks) at best. Some studies show worsened insulin sensitivity and increased oxidative stress. Likely not worth including in most stacks.
Mechanism
Isomers of linoleic acid; proposed modulation of PPAR-γ, SCD-1, lipoprotein lipase; inhibition of adipocyte lipogenesis
Dose & route
3-6 g/day
Citations
- https://pubmed.ncbi.nlm.nih.gov/17490954/
- https://pubmed.ncbi.nlm.nih.gov/17636078/
- https://academic.oup.com/ajcn/article/85/5/1203/4633008
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This is an independent synthesis of published research by a non-clinician. Scores are opinions supported by citations, not prescriptions. See the full disclaimer and methodology for how this score was produced and what it does and doesn't mean.