Rankings / Cardiovascular & Lipids
Garlic extract (aged / allicin)
CV/Lipid · Organosulfur polyphenol
Tier B
What this is
Ried 2008 and subsequent meta-analyses consistent for modest BP reduction. Budoff EBT trials in Kyolic showed slowed coronary calcium progression. Cheap, safe adjunct for patients with mild hypertension who want non-pharma options.
Mechanism
Aged garlic extract (AGE, Kyolic) provides S-allyl cysteine; allicin from crushed raw garlic; multiple proposed mechanisms — ACE inhibition, endothelial NO, mild antiplatelet, cholesterol biosynthesis
Dose & route
600-1200 mg/day aged garlic extract; 180-600 mg/day allicin-standardized
Citations
- https://pubmed.ncbi.nlm.nih.gov/18554422/
- https://pubmed.ncbi.nlm.nih.gov/19138431/
- https://pmc.ncbi.nlm.nih.gov/articles/PMC5651468/
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This is an independent synthesis of published research by a non-clinician. Scores are opinions supported by citations, not prescriptions. See the full disclaimer and methodology for how this score was produced and what it does and doesn't mean.