RAD-140 (testolone)
Muscle & Strength · SARM
Tier D+
Bottom line
Read Off Label grades RAD-140 (testolone) as D+ (3.7/10) based on weak evidence, med-high benefit magnitude, and a med-high-risk safety profile.
Regarded by users as the most 'wet' and strongest SARM — closer to traditional AAS effect profile.
Typical use: Typical illicit: 10-20 mg/day PO — NOT FDA-approved; gray market; banned sport.
What this is
Regarded by users as the most 'wet' and strongest SARM — closer to traditional AAS effect profile. Multiple published case reports of drug-induced liver injury. Radius Health halted clinical development. Aggressive marketing as 'legal steroid' despite clear illicit status.
Mechanism
Strong non-steroidal SARM; high anabolic activity in muscle with reduced prostate effects in preclinical; originally developed by Radius Health for breast cancer and now abandoned
Dose & route
Typical illicit: 10-20 mg/day PO
Citations
- https://pubmed.ncbi.nlm.nih.gov/21521818/
- https://pubmed.ncbi.nlm.nih.gov/32737824/
- https://pubmed.ncbi.nlm.nih.gov/33284089/
Links go to the source. If a link is dead or you want something re-checked, let me know.
Common questions
- Does RAD-140 (testolone) work?
- Read Off Label rates the evidence for RAD-140 (testolone) as Weak and the benefit magnitude as med-high, producing an overall grade of D+ (3.7/10). Regarded by users as the most 'wet' and strongest SARM — closer to traditional AAS effect profile.
- Is RAD-140 (testolone) safe?
- RAD-140 (testolone) has a med-high risk profile in published human data. Legal status: NOT FDA-approved; gray market; banned sport (WADA). This is not medical advice — see the disclaimer.
- What is the typical dose for RAD-140 (testolone)?
- Typical illicit: 10-20 mg/day PO
- How does RAD-140 (testolone) work?
- Strong non-steroidal SARM; high anabolic activity in muscle with reduced prostate effects in preclinical; originally developed by Radius Health for breast cancer and now abandoned
This is an independent synthesis of published research by a non-clinician. Scores are opinions supported by citations, not prescriptions. See the full disclaimer and methodology for how this score was produced and what it does and doesn't mean.