S-23
Muscle Building · SARM
Tier D
What this is
Developed at Kaken Pharmaceutical / GTx as contraceptive. Because it fully suppresses spermatogenesis at moderate doses, 'SARM-like' billing is misleading — closer to an AAS in effect. Limited popularity due to severity of side effect profile.
Mechanism
Strong SARM with high AR binding and full agonist activity in androgenic tissues; originally developed as male hormonal contraceptive candidate
Dose & route
Typical illicit: 10-30 mg/day PO
Citations
- https://pubmed.ncbi.nlm.nih.gov/17356133/
- https://pubmed.ncbi.nlm.nih.gov/14761987/
- https://pubmed.ncbi.nlm.nih.gov/29378245/
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This is an independent synthesis of published research by a non-clinician. Scores are opinions supported by citations, not prescriptions. See the full disclaimer and methodology for how this score was produced and what it does and doesn't mean.