Trenbolone
Muscle & Strength · Injectable 19-nor steroid (~5x androgen activity)
Tier C
Bottom line
Read Off Label grades Trenbolone as C (5.1/10) based on strong evidence, very high benefit magnitude, and a very high-risk safety profile.
Not approved for human use anywhere.
Typical use: Illicit: acetate 50-100 mg EOD; enanthate 200-400 mg/week — Schedule III US (when diverted for human use); banned sport.
What this is
Not approved for human use anywhere. Consistently rated by bodybuilders as the harshest AAS for side effects despite strong results. Distinct cardiovascular and renal toxicity beyond what's seen with other AAS. Home-brewed from cattle implants in older illicit markets. Very high Benefit reflects striking anabolic/body-composition effects; very low Safety reflects severe harm potential.
Mechanism
19-nor derivative; ~5x AR binding affinity vs testosterone; does not aromatize; progestogenic; increases IGF-1 locally; veterinary compound (Finaplix cattle pellets)
Dose & route
Illicit: acetate 50-100 mg EOD; enanthate 200-400 mg/week
Citations
- https://pubmed.ncbi.nlm.nih.gov/23896813/
- https://pubmed.ncbi.nlm.nih.gov/29752847/
- https://pubmed.ncbi.nlm.nih.gov/31422540/
- https://www.ncbi.nlm.nih.gov/books/NBK482418/
Links go to the source. If a link is dead or you want something re-checked, let me know.
Common questions
- Does Trenbolone work?
- Read Off Label rates the evidence for Trenbolone as Strong and the benefit magnitude as very high, producing an overall grade of C (5.1/10). Not approved for human use anywhere.
- Is Trenbolone safe?
- Trenbolone has a very high risk profile in published human data. Legal status: Schedule III US (when diverted for human use); banned sport. This is not medical advice — see the disclaimer.
- What is the typical dose for Trenbolone?
- Illicit: acetate 50-100 mg EOD; enanthate 200-400 mg/week
- How does Trenbolone work?
- 19-nor derivative; ~5x AR binding affinity vs testosterone; does not aromatize; progestogenic; increases IGF-1 locally; veterinary compound (Finaplix cattle pellets)
This is an independent synthesis of published research by a non-clinician. Scores are opinions supported by citations, not prescriptions. See the full disclaimer and methodology for how this score was produced and what it does and doesn't mean.