Rankings / Longevity

Longevity — Pharma (Off-Label)

Rapamycin, metformin, acarbose. Prescription drugs with the strongest longevity-in-mammals evidence. Human data is the bottleneck.

Compounds ranked
3
Top-ranked
# Compound Class Ev Bn Sf Ax Grade · Score
1 Metformin
Biguanide
Prescription 8.0 5.0 7.0 6.0 B 6.8
2 Acarbose
Alpha-glucosidase inhibitor
Prescription 6.0 5.0 7.0 6.0 B- 6.0
3 Rapamycin (sirolimus)
mTOR inhibitor
Prescription 4.5 6.5 5.0 6.0 C+ 5.3

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