Rankings / Cognitive — Nootropics
Armodafinil
Cognitive · Wakefulness-promoting
Tier B+
methylationcontrolled-substanceprescription
7.2 / 10
Tier B+
Ev 8.0 Bn 6.5 Sf 7.0 Ax 6.0
What this is
Approved 2007. Often preferred over modafinil for steadier afternoon wakefulness. Generics available. Same serious-rash and psychiatric warnings as modafinil.
Mechanism
R-enantiomer of modafinil; same mechanism but longer plasma half-life and more sustained PM plasma levels; marketed as Nuvigil
Dose & route
150-250 mg PO once daily morning
Citations
- https://pubmed.ncbi.nlm.nih.gov/20085382/
- https://pubmed.ncbi.nlm.nih.gov/19954264/
- https://pmc.ncbi.nlm.nih.gov/articles/PMC3183109/
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This is an independent synthesis of published research by a non-clinician. Scores are opinions supported by citations, not prescriptions. See the full disclaimer and methodology for how this score was produced and what it does and doesn't mean.