Rankings / Cognitive — Nootropics
Bacopa monnieri
Cognitive · Ayurvedic adaptogen
Tier B
What this is
Effects are delayed — typically 8-12 weeks to see measurable cognitive benefits. Kongkeaw 2014 meta-analysis confirmed improvements in free recall. Take with fat (lipophilic). Some GI side effects common in first weeks.
Mechanism
Bacosides A&B modulate cholinergic, serotonergic, GABAergic systems; antioxidant, dendritic proliferation; slow-onset cognitive enhancer requiring chronic dosing
Dose & route
300-600 mg/day standardized to 45-55% bacosides, minimum 8-12 weeks
Citations
- https://pubmed.ncbi.nlm.nih.gov/24252493/
- https://pubmed.ncbi.nlm.nih.gov/24533867/
- https://pmc.ncbi.nlm.nih.gov/articles/PMC3746283/
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This is an independent synthesis of published research by a non-clinician. Scores are opinions supported by citations, not prescriptions. See the full disclaimer and methodology for how this score was produced and what it does and doesn't mean.