Rankings / Longevity — Peptides
Epithalon (epitalon)
Longevity · Pineal peptide bioregulator
Tier C
What this is
Most data from Khavinson's Russian St. Petersburg Institute — limited Western peer-review. Claims of telomere lengthening in somatic cells. Interesting hypothesis but long-term cancer risk from telomerase activation unexamined.
Mechanism
Synthetic Ala-Glu-Asp-Gly tetrapeptide (Khavinson); proposed telomerase activation; pineal modulation; restoration of melatonin rhythm
Dose & route
5-10 mg SC/IM daily for 10-20 day courses, 1-2x/year
Citations
- https://pubmed.ncbi.nlm.nih.gov/12374906/
- https://pmc.ncbi.nlm.nih.gov/articles/PMC9565860/
- https://www.gethealthspan.com/research/article/epitalon
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This is an independent synthesis of published research by a non-clinician. Scores are opinions supported by citations, not prescriptions. See the full disclaimer and methodology for how this score was produced and what it does and doesn't mean.