NAC (N-acetyl cysteine)
Base · Supplement
Tier A-
glutathioneotc
7.7 / 10
Tier A-
Ev 8.0 Bn 5.0 Sf 9.0 Ax 10.0
What this is
Core component of GlyNAC longevity combo (with glycine). Used medically IV for acetaminophen overdose. Can cause transient nausea at high doses.
Mechanism
Glutathione precursor (replenishes intracellular GSH); mucolytic (breaks disulfide bonds); glutamate modulation in brain
Dose & route
600-1800 mg/day; higher for acute liver protection
Citations
- https://pmc.ncbi.nlm.nih.gov/articles/PMC8774421/
- https://pubmed.ncbi.nlm.nih.gov/25234283/
- https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD001287.pub6/full
Links go to the source. If a link is dead or you want something re-checked, let me know.
This is an independent synthesis of published research by a non-clinician. Scores are opinions supported by citations, not prescriptions. See the full disclaimer and methodology for how this score was produced and what it does and doesn't mean.