Rankings / Weight Loss — Other
T3 (for fat loss)
Weight loss · Thyroid hormone
Tier B-
What this is
Suppresses endogenous thyroid function with chronic exogenous use. Used in bodybuilding cutting cycles. Not a safe weight-loss strategy in euthyroid individuals. Discontinuation often causes rebound hypothyroidism.
Mechanism
Triiodothyronine raises basal metabolic rate; increases uncoupling protein activity; catabolic effect on muscle and fat; direct mitochondrial effects
Dose & route
Supraphysiologic doses 25-100 mcg/day used illicitly for fat loss
Citations
- https://pubmed.ncbi.nlm.nih.gov/16670164/
- https://pubmed.ncbi.nlm.nih.gov/23565056/
- https://www.thyroid.org/hyperthyroidism/
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