Rankings / Weight Loss
Weight Loss — Other
Stimulants, lipase inhibitors, combination drugs, older agents, and things your gym buddy mentions that we do not recommend.
| # | Compound | Ev | Bn | Sf | Grade · Score |
|---|---|---|---|---|---|
| 1 | Orlistat Lipase inhibitor | 8.0 | 3.5 | 7.0 | B 6.8 |
| 2 | Contrave (bupropion + naltrexone) Combination | 8.0 | 5.0 | 5.0 | B- 6.3 |
| 3 | Phentermine Sympathomimetic | 8.0 | 6.5 | 3.5 | B- 6.3 |
| 4 | Clenbuterol Beta-2 agonist | 8.0 | 8.0 | 2.0 | B- 6.2 |
| 5 | DNP (2,4-dinitrophenol) Mitochondrial uncoupler | 8.0 | 10.0 | 0.0 | B- 6.2 |
| 6 | Tesofensine Triple monoamine reuptake inhibitor | 6.0 | 8.0 | 5.0 | B- 6.1 |
| 7 | T3 (for fat loss) Thyroid hormone | 8.0 | 6.5 | 2.0 | B- 5.9 |
| 8 | Topiramate Anticonvulsant | 8.0 | 5.0 | 3.5 | B- 5.9 |
| 9 | Bimagrumab Activin receptor antagonist | 6.0 | 6.5 | 5.0 | C+ 5.7 |
| 10 | Yohimbine Alpha-2 antagonist | 6.0 | 3.5 | 5.0 | C+ 5.5 |
| 11 | CLA (conjugated linoleic acid) Fatty acid | 4.5 | 2.0 | 7.0 | C 5.1 |
| 12 | Naltrexone (low dose, LDN) Opioid antagonist | 3.0 | 2.0 | 9.0 | C 4.6 |