Rankings / Gut
Gut
Probiotics, prebiotic fibres, digestive enzymes, SCFAs, FMT. Strong in specific clinical scenarios, murkier in healthy adults.
| # | Compound | Ev | Bn | Sf | Grade · Score |
|---|---|---|---|---|---|
| 1 | Psyllium husk Soluble viscous fiber | 8.0 | 8.0 | 9.0 | A 8.5 |
| 2 | Rifaximin (Xifaxan) Gut-selective antibiotic | 8.0 | 8.0 | 9.0 | A- 7.9 |
| 3 | FMT (fecal microbiota transplantation) Microbiome transplant | 10.0 | 8.0 | 5.0 | A- 7.8 |
| 4 | Probiotics (multi-strain) Live microbial supplement | 8.0 | 5.0 | 9.0 | A- 7.7 |
| 5 | Saccharomyces boulardii Probiotic yeast | 8.0 | 5.0 | 9.0 | A- 7.7 |
| 6 | Digestive enzymes (pancreatin / proteases / lipase) Exogenous digestive enzymes | 8.0 | 3.5 | 9.0 | B+ 7.3 |
| 7 | Butyrate (tributyrin / sodium butyrate) Short-chain fatty acid | 6.0 | 5.0 | 9.0 | B 6.9 |
| 8 | Prebiotics (inulin / FOS / GOS / partially hydrolyzed guar gum) Fermentable fibers | 6.0 | 5.0 | 7.0 | B 6.4 |
| 9 | Akkermansia muciniphila (pasteurized) Next-generation probiotic | 6.0 | 3.5 | 9.0 | B- 6.3 |
| 10 | DGL (deglycyrrhizinated licorice) Mucosal protectant | 3.0 | 3.5 | 9.0 | C+ 5.3 |
| 11 | Betaine HCl Gastric acid supplementation | 3.0 | 4.0 | 5.0 | C- 4.5 |
| 12 | Larazotide acetate (AT-1001) Tight junction regulator | 3.0 | 3.0 | 4.0 | D+ 3.4 |