Rankings / Cognitive — Nootropics
9-Me-BC (9-methyl-β-carboline)
Cognitive · Beta-carboline / neurotrophic
Tier D+
What this is
Obscure research chemical. Polanski group showed dopaminergic neuroprotection in mouse Parkinson's models. No human trials. Sold in gray-market nootropic shops with extravagant claims; avoid.
Mechanism
Weak MAOI; proposed to stimulate dopaminergic neurogenesis/neuroprotection; upregulates BDNF, GDNF in preclinical models
Dose & route
No established human dosing
Citations
- https://pubmed.ncbi.nlm.nih.gov/20682326/
- https://pubmed.ncbi.nlm.nih.gov/21094674/
- https://pubmed.ncbi.nlm.nih.gov/29704920/
Links go to the source. If a link is dead or you want something re-checked, let me know.
This is an independent synthesis of published research by a non-clinician. Scores are opinions supported by citations, not prescriptions. See the full disclaimer and methodology for how this score was produced and what it does and doesn't mean.