Rankings / Cognitive

Adrafinil / modafinil analog stimulants

Cognitive · Wakefulness-promoting research chemical

Tier D+

wadastimulantwakefulnessbanned-sport
3.9 / 10
Tier D+
Ev 3.0 Bn 5.0 Sf 4.5

What this is

WADA coverage: adrafinil, fladrafinil, flmodafinil and hydrafinil/fluorenol. Modafinil and armodafinil keep their own Rx rows. Additional WADA alias coverage: Fladrafinil (2-[Bis(4-fluorophenyl)methylsulfinyl]-N-hydroxyacetamide) and Flmodafinil (2-[Bis(4-fluorophenyl)methylsulfinyl]acetamide). Fonturacetam [4-phenylpiracetam (carphedon)] is covered by the dedicated Phenylpiracetam row.

Mechanism

Adrafinil is a prodrug-like predecessor to modafinil; fladrafinil, flmodafinil and hydrafinil are gray-market analogs pursued for wakefulness and focus.

Dose & route

No approved enhancement dose for analogs

Citations

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This is an independent synthesis of published research by a non-clinician. Scores are opinions supported by citations, not prescriptions. See the full disclaimer and methodology for how this score was produced and what it does and doesn't mean.