Rankings / Hormones & Endocrine
GnRH/LH-axis analogs for testosterone stimulation
Hormones & Endocrine · HPG-axis peptide / gonadotropin manipulation
Tier C
What this is
WADA coverage: chorionic gonadotrophin/CG, luteinizing hormone/LH, gonadotrophin-releasing hormone/GnRH/gonadorelin, buserelin, deslorelin, goserelin, histrelin, leuprorelin, nafarelin, triptorelin, kisspeptin and agonist analogues. Existing rows cover HCG, gonadorelin and kisspeptin-10; this row captures the broader WADA class and spelling aliases such as gonadotrophin and clomifene-style nomenclature. Additional WADA alias coverage: Kisspeptin and its agonist analogues.
Mechanism
LH and GnRH analogs can stimulate or suppress gonadal steroid production depending pattern and context; male enhancement use targets endogenous testosterone signaling.
Dose & route
Clinical fertility/endocrine protocols vary; no healthy optimization dose
Citations
- https://www.ncbi.nlm.nih.gov/books/NBK305894/
- https://www.wada-ama.org/en/resources/2026-prohibited-list
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This is an independent synthesis of published research by a non-clinician. Scores are opinions supported by citations, not prescriptions. See the full disclaimer and methodology for how this score was produced and what it does and doesn't mean.