Other WADA-listed stimulants (designer / anorectic / recreational)
Cognitive · Stimulant long tail
Tier D
High-risk evidence profile
Bottom line
Read Off Label grades Other WADA-listed stimulants (designer / anorectic / recreational) as D (2.9/10) based on weak evidence, med benefit magnitude, and a high-risk safety profile.
Its high-risk evidence profile reflects a Safety score of 2/10; reported benefits and harms can differ by indication, dose, route, duration, and population.
WADA coverage: amfepramone/diethylpropion, amfetamine/amfetaminil, amiphenazole, benfluorex, benzylpiperazine/BZP, clobenzorex, cocaine, cropropamide, crotetamide, fencamine, fencamfamin, fenetylline, fenfluramine/norfenfluramine, fenproporex, furfenorex, mefenorex, mephentermine, mesocarb, metamfetamine(d-), p-methylamfetamine, phendimetrazine, prenylamine, prolintane, BMPEA, 3-Methylhexan-2-amine, 4-Methylhexan-2-amine/DMAA/methylhexaneamine, 4-Methylpentan-2-amine/DMBA, 5-Methylhexan-2-amine/1,4-DMAA, benzfetamine, cathinone analogues, mephedrone, methedrone, alpha-pyrrolidinovalerophenone/alpha-PVP, dimetamfetamine, etamivan, etilamfetamine, etilefrine, famprofazone, fenbutrazate, heptaminol, hydroxyamfetamine, isometheptene, levmetamfetamine, meclofenoxate/centrophenoxine, midodrine, nikethamide, norfenefrine, octodrine/DMHA, octopamine, oxilofrine/methylsynephrine, pemoline, pentetrazol, phenethylamine derivatives, phenmetrazine, phenpromethamine, propylhexedrine, sibutramine, strychnine, tenamfetamine/MDA and tuaminoheptane.
Studied, labeled, or reported-use context: No general safe dose — Rx/controlled/illegal/research-chemical status varies; WADA S6 prohibited in competition for listed prohibited stimulants; not individualized guidance.
What the evidence says
WADA coverage: amfepramone/diethylpropion, amfetamine/amfetaminil, amiphenazole, benfluorex, benzylpiperazine/BZP, clobenzorex, cocaine, cropropamide, crotetamide, fencamine, fencamfamin, fenetylline, fenfluramine/norfenfluramine, fenproporex, furfenorex, mefenorex, mephentermine, mesocarb, metamfetamine(d-), p-methylamfetamine, phendimetrazine, prenylamine, prolintane, BMPEA, 3-Methylhexan-2-amine, 4-Methylhexan-2-amine/DMAA/methylhexaneamine, 4-Methylpentan-2-amine/DMBA, 5-Methylhexan-2-amine/1,4-DMAA, benzfetamine, cathinone analogues, mephedrone, methedrone, alpha-pyrrolidinovalerophenone/alpha-PVP, dimetamfetamine, etamivan, etilamfetamine, etilefrine, famprofazone, fenbutrazate, heptaminol, hydroxyamfetamine, isometheptene, levmetamfetamine, meclofenoxate/centrophenoxine, midodrine, nikethamide, norfenefrine, octodrine/DMHA, octopamine, oxilofrine/methylsynephrine, pemoline, pentetrazol, phenethylamine derivatives, phenmetrazine, phenpromethamine, propylhexedrine, sibutramine, strychnine, tenamfetamine/MDA and tuaminoheptane. Additional WADA alias coverage: 2-phenylpropan-1-amine (beta-methylphenylethylamine, BMPEA); Cathinone and its analogues; Methylnaphthidate [(+/-)-methyl-2-(naphthalen-2-yl)-2-(piperidin-2-yl)acetate]; Phenethylamine and its derivatives.
Mechanism
This coverage row captures WADA stimulants not represented by dedicated amphetamine, methylphenidate, modafinil, bromantane, phenylpiracetam, solriamfetol, selegiline, tesofensine, caffeine, nicotine or bupropion pages.
Studied, labeled, or reported dose & route
No general safe dose
This records doses and routes described in studies, approved labeling, clinical practice, or documented use. It is not individualized guidance and does not establish safety; context changes with indication, formulation, health history, monitoring, and other medicines.
Citations
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Common questions
- What does the evidence show about Other WADA-listed stimulants (designer / anorectic / recreational)'s effects?
- Read Off Label rates the evidence for Other WADA-listed stimulants (designer / anorectic / recreational) as Weak and the benefit magnitude as med, producing an overall grade of D (2.9/10). WADA coverage: amfepramone/diethylpropion, amfetamine/amfetaminil, amiphenazole, benfluorex, benzylpiperazine/BZP, clobenzorex, cocaine, cropropamide, crotetamide, fencamine, fencamfamin, fenetylline, fenfluramine/norfenfluramine, fenproporex, furfenorex, mefenorex, mephentermine, mesocarb, metamfetamine(d-), p-methylamfetamine, phendimetrazine, prenylamine, prolintane, BMPEA, 3-Methylhexan-2-amine, 4-Methylhexan-2-amine/DMAA/methylhexaneamine, 4-Methylpentan-2-amine/DMBA, 5-Methylhexan-2-amine/1,4-DMAA, benzfetamine, cathinone analogues, mephedrone, methedrone, alpha-pyrrolidinovalerophenone/alpha-PVP, dimetamfetamine, etamivan, etilamfetamine, etilefrine, famprofazone, fenbutrazate, heptaminol, hydroxyamfetamine, isometheptene, levmetamfetamine, meclofenoxate/centrophenoxine, midodrine, nikethamide, norfenefrine, octodrine/DMHA, octopamine, oxilofrine/methylsynephrine, pemoline, pentetrazol, phenethylamine derivatives, phenmetrazine, phenpromethamine, propylhexedrine, sibutramine, strychnine, tenamfetamine/MDA and tuaminoheptane.
- What safety findings are reported for Other WADA-listed stimulants (designer / anorectic / recreational)?
- Other WADA-listed stimulants (designer / anorectic / recreational) has a high risk profile in the database. High (cardiovascular, psychiatric, overheating, dependence and contamination risks; several are recreational/illicit drugs) Legal status: Rx/controlled/illegal/research-chemical status varies; WADA S6 prohibited in competition for listed prohibited stimulants.
- What does the low Safety score for Other WADA-listed stimulants (designer / anorectic / recreational) represent?
- The Safety score is 2/10. It records the substantial harms described for one or more use contexts; the Benefit score, indication, dose, route, duration, population, and legal status remain separate parts of the evidence profile.
- What doses or routes are reported for Other WADA-listed stimulants (designer / anorectic / recreational)?
- No general safe dose This is context from studies, approved labeling, clinical practice, or documented use; it is not individualized guidance and does not establish safety.
- How does Other WADA-listed stimulants (designer / anorectic / recreational) work?
- This coverage row captures WADA stimulants not represented by dedicated amphetamine, methylphenidate, modafinil, bromantane, phenylpiracetam, solriamfetol, selegiline, tesofensine, caffeine, nicotine or bupropion pages.
This is an independent synthesis of published research by a non-clinician. Scores are opinions supported by citations, not prescriptions. See the full disclaimer and methodology for how this score was produced and what it does and doesn't mean.