Oxiracetam
Cognitive · Racetam
Tier B
Bottom line
Read Off Label grades Oxiracetam as B (6.4/10) based on weak-moderate evidence, variable benefit magnitude, and a low-risk safety profile.
Italian/Chinese clinical use for multi-infarct dementia.
Studied, labeled, or reported-use context: 1200-2400 mg/day PO divided — Rx in Italy/China; research chem in US; not individualized guidance.
What the evidence says
Italian/Chinese clinical use for multi-infarct dementia. Fewer side effects than piracetam reported. More stimulating profile — users sometimes dose only in the morning.
Mechanism
Structural analog of piracetam with additional hydroxyl group; enhances acetylcholine release; AMPA-positive modulation; described as mildly stimulating
Studied, labeled, or reported dose & route
1200-2400 mg/day PO divided
This records doses and routes described in studies, approved labeling, clinical practice, or documented use. It is not individualized guidance and does not establish safety; context changes with indication, formulation, health history, monitoring, and other medicines.
Citations
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Common questions
- What does the evidence show about Oxiracetam's effects?
- Read Off Label rates the evidence for Oxiracetam as Weak-Moderate and the benefit magnitude as variable, producing an overall grade of B (6.4/10). Italian/Chinese clinical use for multi-infarct dementia.
- What safety findings are reported for Oxiracetam?
- Oxiracetam has a low risk profile in the database. Low (reported) Legal status: Rx in Italy/China; research chem in US.
- What doses or routes are reported for Oxiracetam?
- 1200-2400 mg/day PO divided This is context from studies, approved labeling, clinical practice, or documented use; it is not individualized guidance and does not establish safety.
- How does Oxiracetam work?
- Structural analog of piracetam with additional hydroxyl group; enhances acetylcholine release; AMPA-positive modulation; described as mildly stimulating
This is an independent synthesis of published research by a non-clinician. Scores are opinions supported by citations, not prescriptions. See the full disclaimer and methodology for how this score was produced and what it does and doesn't mean.