P21 peptide
Cognitive · Peptide (CNTF analog)
Tier D
Bottom line
Read Off Label grades P21 peptide as D (3.3/10) based on preclinical only evidence, unclear benefit magnitude, and a unclear-risk safety profile.
Derived from Iqbal lab work at NYS Institute for Basic Research.
Studied, labeled, or reported-use context: No established human dosing — Research chem; not individualized guidance.
What the evidence says
Derived from Iqbal lab work at NYS Institute for Basic Research. Preclinical mouse data on learning and neurogenesis. No published human trials. Sold by gray-market peptide vendors despite minimal evidence.
Mechanism
Synthetic 4-amino-acid peptide derived from ciliary neurotrophic factor (CNTF); proposed to stimulate neurogenesis via CNTF receptor pathway
Studied, labeled, or reported dose & route
No established human dosing
This records doses and routes described in studies, approved labeling, clinical practice, or documented use. It is not individualized guidance and does not establish safety; context changes with indication, formulation, health history, monitoring, and other medicines.
Citations
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Common questions
- What does the evidence show about P21 peptide's effects?
- Read Off Label rates the evidence for P21 peptide as Preclinical only and the benefit magnitude as unclear, producing an overall grade of D (3.3/10). Derived from Iqbal lab work at NYS Institute for Basic Research.
- What safety findings are reported for P21 peptide?
- P21 peptide has a unclear risk profile in the database. Unknown (no human safety data) Legal status: Research chem.
- What doses or routes are reported for P21 peptide?
- No established human dosing This is context from studies, approved labeling, clinical practice, or documented use; it is not individualized guidance and does not establish safety.
- How does P21 peptide work?
- Synthetic 4-amino-acid peptide derived from ciliary neurotrophic factor (CNTF); proposed to stimulate neurogenesis via CNTF receptor pathway
This is an independent synthesis of published research by a non-clinician. Scores are opinions supported by citations, not prescriptions. See the full disclaimer and methodology for how this score was produced and what it does and doesn't mean.