Rankings / Cognitive — Nootropics
Selank
Cognitive · Russian peptide
Tier C
What this is
Claimed to reduce anxiety without the sedation or dependence of benzodiazepines. Russian trials in generalized anxiety disorder. Very limited Western replication. Often stacked with Semax.
Mechanism
Synthetic analog of tuftsin; anxiolytic via GABAergic modulation; increases BDNF; enkephalin modulation — atypical anxiolytic without sedation
Dose & route
300-1500 mcg intranasal daily
Citations
- https://pubmed.ncbi.nlm.nih.gov/19639854/
- https://pubmed.ncbi.nlm.nih.gov/19621276/
- https://pmc.ncbi.nlm.nih.gov/articles/PMC7232131/
Links go to the source. If a link is dead or you want something re-checked, let me know.
This is an independent synthesis of published research by a non-clinician. Scores are opinions supported by citations, not prescriptions. See the full disclaimer and methodology for how this score was produced and what it does and doesn't mean.