Rankings / Diagnostics

Diagnostics

Labs, imaging, wearables, and screening tools that inform the other interventions. Scored on utility rather than "effectiveness" in the drug sense.

Compounds ranked
16
# Compound Class Ev Bn Sf Ax Grade · Score
1 Advanced lipid panel (ApoB + Lp(a))
Cardiovascular risk
Diagnostic 10.0 10.0 10.0 6.0 S 9.6
2 DEXA scan (bone density + body composition)
Imaging
Diagnostic 10.0 10.0 10.0 6.0 S 9.6
3 Ferritin + iron panel
Iron status
Diagnostic 10.0 10.0 10.0 6.0 S 9.6
4 HbA1c / fasting insulin / HOMA-IR
Glycemic / insulin status
Diagnostic 10.0 10.0 10.0 6.0 S 9.6
5 Standard annual bloodwork (CBC + CMP)
Core labs
Diagnostic 10.0 10.0 10.0 6.0 S 9.6
6 Coronary artery calcium score (CAC)
CV imaging
Diagnostic 10.0 10.0 9.0 5.0 A+ 9.3
7 VO2max testing (cardiopulmonary exercise test)
Cardiorespiratory fitness
Diagnostic 10.0 10.0 9.0 5.0 A+ 9.3
8 Thyroid panel (TSH + free T4 + free T3 + antibodies + reverse T3)
Thyroid function
Diagnostic 10.0 8.0 10.0 6.0 A+ 9.1
9 hs-CRP (high-sensitivity C-reactive protein)
Inflammatory marker
Diagnostic 8.0 8.0 10.0 6.0 A 8.3
10 Sex hormones (total/free T, SHBG, E2, LH/FSH, DHEA-S)
HPG axis
Diagnostic 8.0 8.0 10.0 6.0 A 8.3
11 Vitamin D (25-OH-D)
Vitamin D status
Vitamin 8.0 8.0 10.0 6.0 A 8.3
12 Continuous glucose monitor (CGM — Dexcom / Libre / Stelo)
Real-time glucose
Diagnostic 8.0 5.0 9.0 6.0 B+ 7.3
13 Homocysteine
Methylation / B-vitamin status
Diagnostic 6.0 5.0 10.0 6.0 B 6.8
14 Epigenetic age testing (GrimAge / Horvath / TruAge)
Biological age
Diagnostic 6.0 5.0 9.0 5.0 B 6.4
15 Whole-body MRI (Prenuvo / Ezra)
Screening imaging
Diagnostic 4.5 5.0 5.0 3.0 C 4.6
16 Multi-cancer early detection (Galleri)
Blood-based cancer screening
Diagnostic 4.5 3.0 5.0 3.0 C- 4.1

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