DMSA / DMPS (heavy metal chelators)
Detox · Sulfhydryl chelators
Tier B
What this is
'Mercury toxicity from fillings' is largely pseudoscience driving unnecessary chelation with real iatrogenic risk. Autism chelation protocols (Geier DMPS) are thoroughly discredited. Legitimate role limited to confirmed elevated blood lead (especially pediatric) or acute heavy metal poisoning. Provocative urine tests are not a valid indication.
Mechanism
2,3-dimercaptosuccinic acid (DMSA/Succimer — oral) and 2,3-dimercaptopropane-1-sulfonate (DMPS — IV/oral); thiol groups bind heavy metals (lead, mercury, arsenic) for renal excretion
Dose & route
Protocols vary by agent and severity; medical supervision required
Citations
- https://pubmed.ncbi.nlm.nih.gov/15082607/
- https://pubmed.ncbi.nlm.nih.gov/18534407/
- https://pmc.ncbi.nlm.nih.gov/articles/PMC3122039/
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