Modified citrus pectin (MCP)
Detox · Galactose-rich polysaccharide
Tier C+
Bottom line
Read Off Label grades Modified citrus pectin (MCP) as C+ (5.5/10) based on weak evidence, low-med benefit magnitude, and a low-risk safety profile.
PectaSol-C (Eliaz) is the most-studied commercial formulation.
Studied, labeled, or reported-use context: 5-15 g/day PO — OTC; not individualized guidance.
What the evidence says
PectaSol-C (Eliaz) is the most-studied commercial formulation. Heavy metal chelation data is thin but intriguing. Galectin-3 modulation has growing interest in cardiovascular and oncology contexts. More rationale than proof at present.
Mechanism
Pectin chemically modified (hydrolyzed to lower molecular weight) from citrus peel; binds galectin-3 extracellularly; proposed heavy metal chelator; anti-metastasis signal in cancer preclinical
Studied, labeled, or reported dose & route
5-15 g/day PO
This records doses and routes described in studies, approved labeling, clinical practice, or documented use. It is not individualized guidance and does not establish safety; context changes with indication, formulation, health history, monitoring, and other medicines.
Citations
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Common questions
- What does the evidence show about Modified citrus pectin (MCP)'s effects?
- Read Off Label rates the evidence for Modified citrus pectin (MCP) as Weak and the benefit magnitude as low-med, producing an overall grade of C+ (5.5/10). PectaSol-C (Eliaz) is the most-studied commercial formulation.
- What safety findings are reported for Modified citrus pectin (MCP)?
- Modified citrus pectin (MCP) has a low risk profile in the database. Low (generally well-tolerated; GI upset occasionally) Legal status: OTC.
- What doses or routes are reported for Modified citrus pectin (MCP)?
- 5-15 g/day PO This is context from studies, approved labeling, clinical practice, or documented use; it is not individualized guidance and does not establish safety.
- How does Modified citrus pectin (MCP) work?
- Pectin chemically modified (hydrolyzed to lower molecular weight) from citrus peel; binds galectin-3 extracellularly; proposed heavy metal chelator; anti-metastasis signal in cancer preclinical
This is an independent synthesis of published research by a non-clinician. Scores are opinions supported by citations, not prescriptions. See the full disclaimer and methodology for how this score was produced and what it does and doesn't mean.