Rankings / Toxins

TCE (trichloroethylene)

Toxins · Chlorinated solvent

High exposure concern

water-contaminantbanned
8 / 10
HIGH
Mag 8 Ev 8 Prev 8

Bottom line

Read Off Label rates TCE (trichloroethylene) a HIGH exposure concern (8.0/10) based on strong evidence of high harm magnitude and high occupational/exposed exposure prevalence.

EPA December 2024 final rule banning most TCE uses under TSCA — major regulatory action.

This entry describes an exposure rather than an added intervention.

What the evidence says

EPA December 2024 final rule banning most TCE uses under TSCA — major regulatory action. Vapor intrusion (groundwater contamination entering homes through sub-slab) is an often-overlooked exposure route. Parkinson's association (Goldman 2023) has gained substantial evidence — Camp Lejeune cohort showed elevated PD risk.

Mechanism

Industrial degreasing solvent; widespread groundwater contaminant near industrial/military sites (Camp Lejeune); IARC Group 1; established Parkinson's risk signal

Reported exposure / mitigation context

EPA Superfund maps; drinking water testing near industrial sites; vapor intrusion mitigation in affected homes

Citations

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Common questions

How harmful is TCE (trichloroethylene)?
TCE (trichloroethylene) is rated HIGH exposure concern (8.0/10) on the Read Off Label scale, derived from strong evidence of high harm magnitude and high occupational/exposed exposure prevalence.
How does TCE (trichloroethylene) cause harm?
Industrial degreasing solvent; widespread groundwater contaminant near industrial/military sites (Camp Lejeune); IARC Group 1; established Parkinson's risk signal
What exposure context is reported for TCE (trichloroethylene)?
EPA December 2024 final rule banning most TCE uses under TSCA — major regulatory action.

This is an independent synthesis of published research by a non-clinician. Scores are opinions supported by citations, not prescriptions. See the full disclaimer and methodology for how this score was produced and what it does and doesn't mean.