TCE (trichloroethylene)
Toxins · Chlorinated solvent
High priority
Bottom line
Read Off Label rates TCE (trichloroethylene) a HIGH avoidance priority (8.0/10) based on strong evidence of high harm magnitude and high occupational/exposed exposure prevalence.
EPA December 2024 final rule banning most TCE uses under TSCA — major regulatory action.
The intervention here is reducing exposure, not adding a compound.
What this is
EPA December 2024 final rule banning most TCE uses under TSCA — major regulatory action. Vapor intrusion (groundwater contamination entering homes through sub-slab) is an often-overlooked exposure route. Parkinson's association (Goldman 2023) has gained substantial evidence — Camp Lejeune cohort showed elevated PD risk.
Mechanism
Industrial degreasing solvent; widespread groundwater contaminant near industrial/military sites (Camp Lejeune); IARC Group 1; established Parkinson's risk signal
Dose & route
EPA Superfund maps; drinking water testing near industrial sites; vapor intrusion mitigation in affected homes
Citations
- https://pubmed.ncbi.nlm.nih.gov/37365881/
- https://www.epa.gov/assessing-and-managing-chemicals-under-tsca/final-risk-management-rule-trichloroethylene-tce
- https://pmc.ncbi.nlm.nih.gov/articles/PMC9979630/
Links go to the source. If a link is dead or you want something re-checked, let me know.
Common questions
- How harmful is TCE (trichloroethylene)?
- TCE (trichloroethylene) is rated HIGH avoidance priority (8.0/10) on the Read Off Label scale, derived from strong evidence of high harm magnitude and high occupational/exposed exposure prevalence.
- How does TCE (trichloroethylene) cause harm?
- Industrial degreasing solvent; widespread groundwater contaminant near industrial/military sites (Camp Lejeune); IARC Group 1; established Parkinson's risk signal
- How do you reduce exposure to TCE (trichloroethylene)?
- EPA December 2024 final rule banning most TCE uses under TSCA — major regulatory action.
This is an independent synthesis of published research by a non-clinician. Scores are opinions supported by citations, not prescriptions. See the full disclaimer and methodology for how this score was produced and what it does and doesn't mean.