Rankings / Toxins

Toxins

Air, water, food, and lifestyle exposures with evidence for harm. Everything here scores poorly by design — the "intervention" is reducing exposure.

Compounds ranked
36
# Compound Class Ev Mag Prev Priority · Score
1 Chronic sleep deprivation
Lifestyle
Lifestyle exposure 10.0 10.0 10.0 CRITICAL 10.0
2 Loneliness / social isolation
Lifestyle
Lifestyle exposure 10.0 10.0 10.0 CRITICAL 10.0
3 Sedentary behavior / sitting
Lifestyle
Lifestyle exposure 10.0 10.0 10.0 CRITICAL 10.0
4 Tobacco smoke (direct / secondhand)
Combustion complex
Lifestyle exposure 10.0 10.0 10.0 CRITICAL 10.0
5 Aflatoxins
Mycotoxin
Mycotoxin 10.0 10.0 5.0 CRITICAL 8.5
6 Alcohol (ethanol)
Neurotoxic psychoactive
Lifestyle exposure 10.0 10.0 5.0 CRITICAL 8.5
7 Lead
Heavy metal / neurotoxicant
Heavy metal 10.0 10.0 5.0 CRITICAL 8.5
8 PM2.5 (fine particulate matter)
Air pollution
Air pollutant 10.0 10.0 5.0 CRITICAL 8.5
9 Radon
Radioactive gas
Air pollutant 10.0 10.0 5.0 CRITICAL 8.5
10 PFAS (PFOA / PFOS / GenX)
Forever chemicals
Endocrine disruptor 8.0 10.0 5.0 HIGH 7.9
11 Benzene
Volatile organic compound
Air pollutant 10.0 8.0 5.0 HIGH 7.7
12 Arsenic
Metalloid / IARC Group 1
Heavy metal 8.0 8.0 5.0 HIGH 7.1
13 Chronic psychological stress
Lifestyle
Lifestyle exposure 8.0 8.0 5.0 HIGH 7.1
14 Fluoride (high-dose)
Controversial
Water contaminant 8.0 8.0 5.0 HIGH 7.1
15 Formaldehyde
VOC / IARC Group 1
Air pollutant 8.0 8.0 5.0 HIGH 7.1
16 NO2 (nitrogen dioxide)
Air pollution
Air pollutant 8.0 8.0 5.0 HIGH 7.1
17 Organophosphate pesticides (chlorpyrifos / malathion)
Acetylcholinesterase inhibitor
Pesticide 8.0 8.0 5.0 HIGH 7.1
18 Ozone (tropospheric)
Air pollution
Air pollutant 8.0 8.0 5.0 HIGH 7.1
19 TCE (trichloroethylene)
Chlorinated solvent
Air pollutant 8.0 8.0 5.0 HIGH 7.1
20 Phthalates (DEHP / DBP / BBP / DEP)
Endocrine disruptor
Endocrine disruptor 7.0 6.5 5.0 MODERATE 6.2
21 Blue light (evening artificial light at night)
Circadian disruptor
Lifestyle exposure 8.0 5.0 5.0 MODERATE 5.9
22 Cadmium
Heavy metal / nephrotoxicant
Heavy metal 8.0 5.0 5.0 MODERATE 5.9
23 Mercury (methylmercury)
Heavy metal / neurotoxicant
Heavy metal 8.0 5.0 5.0 MODERATE 5.9
24 Neonicotinoids (imidacloprid / clothianidin)
Neurotoxic insecticide
Pesticide 8.0 5.0 5.0 MODERATE 5.9
25 PAHs (polycyclic aromatic hydrocarbons — grilled meats, air)
Combustion carcinogen
Cooking byproduct 8.0 5.0 5.0 MODERATE 5.9
26 PBDEs (polybrominated diphenyl ethers)
Flame retardant
Endocrine disruptor 8.0 5.0 3.0 MODERATE 5.3
27 BPA / BPS / BPF (bisphenols)
Endocrine disruptor
Endocrine disruptor 6.0 5.0 5.0 MODERATE 5.3
28 Acrylamide (high-heat cooking)
Maillard byproduct
Cooking byproduct 6.0 3.5 5.0 MODERATE 4.7
29 DBPs (disinfection byproducts — trihalomethanes, haloacetic acids)
Chlorination byproducts
Endocrine disruptor 6.0 3.5 5.0 MODERATE 4.7
30 Ochratoxin A
Mycotoxin
Mycotoxin 6.0 3.5 5.0 MODERATE 4.7
31 EMF / RF exposure (cell phones, Wi-Fi)
Non-ionizing radiation
Lifestyle exposure 4.5 4.0 5.0 MODERATE 4.5
32 Aluminum
Widespread metal
Heavy metal 4.5 3.5 5.0 MODERATE 4.3
33 Triclosan / triclocarban
Antimicrobial
Endocrine disruptor 6.0 3.5 3.0 MODERATE 4.1
34 Microplastics / nanoplastics
Emerging contaminant
Water contaminant 3.0 4.0 5.0 MODERATE 4.0
35 Glyphosate (Roundup)
Broad-spectrum herbicide
Pesticide 3.0 5.0 3.0 LOW 3.8
36 Parabens (methyl / propyl / butyl)
Preservative / weak estrogen
Endocrine disruptor 4.5 3.5 3.0 LOW 3.7

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