Rankings / Libido

Libido

Prescription and botanical options for sexual function. PDE5 inhibitors anchor the list; the rest is a mix of real mechanism and wishful thinking.

Compounds ranked
11
Top-ranked
# Compound Class Ev Bn Sf Ax Grade · Score
1 Tadalafil (Cialis)
Long-acting PDE5 inhibitor
Prescription 10.0 10.0 7.0 6.0 A+ 8.9
2 Sildenafil (Viagra)
PDE5 inhibitor
Prescription 10.0 10.0 5.0 6.0 A 8.4
3 Cabergoline
Dopamine D2 agonist
Prescription 8.0 8.0 5.0 6.0 B+ 7.1
4 Maca (Lepidium meyenii)
Andean cruciferous tuber
Herbal 6.0 3.5 9.0 10.0 B 6.5
5 Tongkat ali (Eurycoma longifolia)
Adaptogen / T-optimizer
Herbal 6.0 3.5 9.0 10.0 B 6.5
6 PT-141 (Bremelanotide / Vyleesi)
Melanocortin receptor agonist
Prescription 6.0 5.0 5.0 6.0 C+ 5.5
7 Yohimbine
Alpha-2 adrenergic antagonist
Prescription 6.0 5.0 3.5 10.0 C+ 5.5
8 Tribulus terrestris
Saponin-containing herb
Herbal 3.0 3.5 9.0 10.0 C+ 5.3
9 Kisspeptin-10
Hypothalamic peptide
Peptide 4.5 3.5 9.0 3.0 C+ 5.2
10 Melanotan II (MT-II)
Non-selective melanocortin agonist
Prescription 6.0 6.5 2.0 4.0 C 4.9
11 Fadogia agrestis
Nigerian shrub
Herbal 3.0 5.0 4.0 10.0 C- 4.5

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