Lutein + zeaxanthin
Eye · Macular carotenoids
Tier A-
What this is
AREDS2 (2013) established the clinical reference formula for AMD risk reduction. Dietary intake from kale, spinach, egg yolks may be sufficient for many. Macular pigment optical density (MPOD) testing measures the relevant outcome. Take with fat for absorption.
Mechanism
Xanthophyll carotenoids concentrated in macula; absorb damaging blue light; antioxidant; dietary sources leafy greens, egg yolks; meso-zeaxanthin formed in retina from lutein
Dose & route
10 mg lutein + 2 mg zeaxanthin daily with fat (AREDS2 dose)
Citations
- https://pubmed.ncbi.nlm.nih.gov/23644932/
- https://pubmed.ncbi.nlm.nih.gov/33077001/
- https://pmc.ncbi.nlm.nih.gov/articles/PMC5579483/
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This is an independent synthesis of published research by a non-clinician. Scores are opinions supported by citations, not prescriptions. See the full disclaimer and methodology for how this score was produced and what it does and doesn't mean.