Rankings / Longevity
Longevity — Supplements
NAD+ precursors, urolithin A, alpha-ketoglutarate, astaxanthin — the over-the-counter longevity supplement aisle.
| # | Compound | Ev | Bn | Sf | Grade · Score |
|---|---|---|---|---|---|
| 1 | Urolithin A Mitophagy inducer | 6.0 | 6.5 | 9.0 | B+ 7.3 |
| 2 | Alpha-ketoglutarate (Ca-AKG) TCA cycle intermediate | 6.0 | 5.0 | 9.0 | B 6.9 |
| 3 | Astaxanthin Carotenoid / antioxidant | 6.0 | 5.0 | 9.0 | B 6.9 |
| 4 | Glycine + NAC (GlyNAC) Amino acid combo | 6.0 | 5.0 | 9.0 | B 6.9 |
| 5 | NAD+ / NMN / NR NAD+ precursor | 6.0 | 5.0 | 9.0 | B 6.9 |
| 6 | Sulforaphane Nrf2 activator | 6.0 | 5.0 | 9.0 | B 6.9 |
| 7 | Hydrogen water / molecular hydrogen (H2) Antioxidant gas | 6.0 | 3.5 | 9.0 | B 6.5 |
| 8 | Lithium (microdose) Alkali metal (trace) | 6.0 | 3.5 | 9.0 | B 6.5 |
| 9 | Berberine AMPK activator | 6.0 | 5.0 | 7.0 | B 6.4 |
| 10 | Pyrroloquinoline quinone (PQQ) Mitochondrial biogenesis cofactor | 4.5 | 3.5 | 9.0 | B- 5.9 |
| 11 | Ergothioneine Fungal amino acid | 3.0 | 5.0 | 9.0 | C+ 5.7 |
| 12 | 17-alpha estradiol Non-feminizing estrogen | 2.0 | 5.0 | 7.0 | C- 4.1 |
| 13 | GDF11 Circulating factor | 2.0 | 5.0 | 5.0 | D+ 3.7 |
| 14 | Klotho Anti-aging protein | 2.0 | 5.0 | 5.0 | D+ 3.7 |
| 15 | Plasma exchange / young plasma Dilutional therapeutic | 2.0 | 5.0 | 3.5 | D+ 3.4 |
| 16 | Yamanaka factors / partial reprogramming Epigenetic reprogramming | 2.0 | 5.0 | 3.5 | D+ 3.4 |
| 17 | C60 (carbon 60 / buckminsterfullerene) Fullerene / antioxidant | 3.0 | 2.0 | 4.0 | D 3.0 |