What does the evidence show about C60 (carbon 60 / buckminsterfullerene)'s effects?

Read Off Label rates the evidence for C60 (carbon 60 / buckminsterfullerene) as Weak and the benefit magnitude as low / varies, producing an overall grade of D (3.3/10). Baati 2012 claimed ~90% lifespan extension in rats with C60-olive oil — results never independently replicated despite attempts.

What safety findings are reported for C60 (carbon 60 / buckminsterfullerene)?

C60 (carbon 60 / buckminsterfullerene) has a unclear risk profile in the database. Unknown (long-term safety untested) Legal status: Research chemical / OTC.

What doses or routes are reported for C60 (carbon 60 / buckminsterfullerene)?

No established human dosing; usually 10-20 mg C60 in olive oil as anecdotal protocol This is context from studies, approved labeling, clinical practice, or documented use; it is not individualized guidance and does not establish safety.

Rankings / Longevity — Supplements

C60 (carbon 60 / buckminsterfullerene)

Longevity · Fullerene / antioxidant

Tier D

Reviewed by Read Off Label · Last reviewed Jun 8, 2026 · How we grade

antioxidantresearch-onlyotc

3.3 / 10

Tier D

Ev 3 Bn 2 Sf 4

Bottom line

Read Off Label grades C60 (carbon 60 / buckminsterfullerene) as D (3.3/10) based on weak evidence, low / varies benefit magnitude, and a unclear-risk safety profile.

Baati 2012 claimed ~90% lifespan extension in rats with C60-olive oil — results never independently replicated despite attempts.

Studied, labeled, or reported-use context: No established human dosing; usually 10-20 mg C60 in olive oil as anecdotal protocol — Research chemical / OTC; not individualized guidance.

What the evidence says

Baati 2012 claimed ~90% lifespan extension in rats with C60-olive oil — results never independently replicated despite attempts. Popular in DIY longevity circles anyway. No human trials. Purity varies dramatically among sellers.

Mechanism

Soccer-ball-shaped carbon cluster; proposed free radical 'sponge'; dissolved in olive oil for oral use; controversial lifespan study in rats (Baati 2012)

Studied, labeled, or reported dose & route

No established human dosing; usually 10-20 mg C60 in olive oil as anecdotal protocol

This records doses and routes described in studies, approved labeling, clinical practice, or documented use. It is not individualized guidance and does not establish safety; context changes with indication, formulation, health history, monitoring, and other medicines.

Citations

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Common questions

What does the evidence show about C60 (carbon 60 / buckminsterfullerene)'s effects?: Read Off Label rates the evidence for C60 (carbon 60 / buckminsterfullerene) as Weak and the benefit magnitude as low / varies, producing an overall grade of D (3.3/10). Baati 2012 claimed ~90% lifespan extension in rats with C60-olive oil — results never independently replicated despite attempts.
What safety findings are reported for C60 (carbon 60 / buckminsterfullerene)?: C60 (carbon 60 / buckminsterfullerene) has a unclear risk profile in the database. Unknown (long-term safety untested) Legal status: Research chemical / OTC.
What doses or routes are reported for C60 (carbon 60 / buckminsterfullerene)?: No established human dosing; usually 10-20 mg C60 in olive oil as anecdotal protocol This is context from studies, approved labeling, clinical practice, or documented use; it is not individualized guidance and does not establish safety.
How does C60 (carbon 60 / buckminsterfullerene) work?: Soccer-ball-shaped carbon cluster; proposed free radical 'sponge'; dissolved in olive oil for oral use; controversial lifespan study in rats (Baati 2012)

This is an independent synthesis of published research by a non-clinician. Scores are opinions supported by citations, not prescriptions. See the full disclaimer and methodology for how this score was produced and what it does and doesn't mean.