Rankings / Longevity — Supplements
Plasma exchange / young plasma
Longevity · Dilutional therapeutic
Tier D+
What this is
Conboy lab 2020 showed neutral saline + albumin exchange had similar rejuvenating effects as young plasma — suggests dilution-based mechanism. FDA 2019 warning against Ambrosia-style young plasma transfusions for anti-aging.
Mechanism
Therapeutic plasma exchange (TPE) removes pro-aging factors (dilution of 'bad' blood) OR replaces with young plasma; Conboy lab shows dilution alone may be sufficient
Dose & route
Clinical TPE protocols — weekly for several sessions
Citations
- https://www.aging-us.com/article/103418/text
- https://www.fda.gov/consumers/consumer-updates/younger-blood-does-not-make-you-younger-or-healthier
- https://pubmed.ncbi.nlm.nih.gov/30022616/
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This is an independent synthesis of published research by a non-clinician. Scores are opinions supported by citations, not prescriptions. See the full disclaimer and methodology for how this score was produced and what it does and doesn't mean.